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quantaphase ii folate vitamin b12 radioassay kit  (Bio-Rad)


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    Structured Review

    Bio-Rad quantaphase ii folate vitamin b12 radioassay kit
    Quantaphase Ii Folate Vitamin B12 Radioassay Kit, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1868 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/quantaphase+ii+folate+assay+kit/Bio-Rad+Protein+Assay+Kit+II/pmc12405778-105-10-16
    Average 96 stars, based on 1868 article reviews
    quantaphase ii folate vitamin b12 radioassay kit - by Bioz Stars, 2026-09
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    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Cochrane Database of System atic Review s Fortification of w heat and m aize flour w ith folic acid for population health outcom es (Review ) Copyright © 2019 The Cochrane Collaboration.. Published by John W iley & Sons, Ltd. 84 baseline and follow-up) (58 to 76 years) 6 older adults participants selected from household of women residing near the hospital throcyte folate < 160 ng/ mL (author's cut-oI): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants ly would receive 500 μg folic acid/ day brand et al 1966) Hertrampf 2003 WheatWheat flour fortified with folic acid and B-vitamins Unontrolled before-andafter (same participants at baseline and follow-up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 7513 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/ kg QuantaPhase II Folate Assay kit (BioRad Laboratories, Hercules, CA) 427 ± 18 μg/ day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Haemoglobin remained unchanged.Haemoglobin remained unchanged.. Serum folate not reported due to wide variations Hertrampf 2003 Wheat Wheat flour fortified with folic acid and B‐vitamins Unontrolled before‐and‐after (same participants at baseline and follow‐up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 751 3 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/kg QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) 427 ± 18 μg/day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707..

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Colman 1974c , Maize , Maize flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Pregnant/lactating women (16 to 33 years), oldest women in household (58 to 76 years) , 5 pregnant women, 1 lactating woman, 6 older adults , Johnson Memorial Hospital at Nqutu, KwaZulu in South Africa. Older participants selected from household of women residing near the hospital , Study reported individual measurements. Erythrocyte folate < 151 ng/mL (WHO): 2/12 participants; erythrocyte folate < 160 ng/mL (author's cut‐off): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants , 6 weeks , Not specified , Enough so that each adult in the family would receive 500 μg folic acid/day , Microbiological assay with Lactobacillus casei (method of Hoffbrand et al 1966) , 500 μg/day , Haemoglobin, erythrocyte cell folate, serum folate , After 6 weeks, there was a significant rise in the erythrocyte folate concentration in 9 of the 12 subjects receiving the fortified food. Haemoglobin remained unchanged. Serum folate not reported due to wide variations.. Hertrampf 2003 , Wheat , Wheat flour fortified with folic acid and B‐vitamins , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service , 751 , 3 outpatient clinics in Santiago, Chile , Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% , approximately 1 year , Not specified , 2.2 mg/kg , QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) , 427 ± 18 μg/day , Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) , Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L . Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L. The prevalence of low serum and RBC folate was not significantly different.. Hirsch 2002 , Wheat , Wheat flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Free‐living adults >/= 70 years of age, with low income , 149 , 3 outpatient clinics in Santiago, Chile , Folate deficiency (serum folate < 6.8 nmol/L): 1.8% , 6 months , Not specified , 220 µg/100 g flour , Anion capture technique using Abbott Laboratories, Diagnostic Division, Abbot Park, IL , Not specified , Serum folate, haemoglobin, serum homocysteine, folate deficiency (< 6.8 nmol/L), hyperhomocysteinaemia , Serum folate increased from mean ± SD 16.2 ± 6.2 nmol/L to 32.7 ± 7.1 nmol/L. Homocysteine decreased from mean ± SD 12.95 ± 3.7 μmol/L to 11.43 ± 3.6 μmol/L. The prevalence of hyperhomocysteinaemia decreased from 31% to 17%.

    Microbial Assay:

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Cochrane Database of System atic Review s Fortification of w heat and m aize flour w ith folic acid for population health outcom es (Review ) Copyright © 2019 The Cochrane Collaboration.. Published by John W iley & Sons, Ltd. 84 baseline and follow-up) (58 to 76 years) 6 older adults participants selected from household of women residing near the hospital throcyte folate < 160 ng/ mL (author's cut-oI): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants ly would receive 500 μg folic acid/ day brand et al 1966) Hertrampf 2003 WheatWheat flour fortified with folic acid and B-vitamins Unontrolled before-andafter (same participants at baseline and follow-up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 7513 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/ kg QuantaPhase II Folate Assay kit (BioRad Laboratories, Hercules, CA) 427 ± 18 μg/ day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Haemoglobin remained unchanged.Haemoglobin remained unchanged.. Serum folate not reported due to wide variations Hertrampf 2003 Wheat Wheat flour fortified with folic acid and B‐vitamins Unontrolled before‐and‐after (same participants at baseline and follow‐up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 751 3 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/kg QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) 427 ± 18 μg/day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707..

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Colman 1974c , Maize , Maize flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Pregnant/lactating women (16 to 33 years), oldest women in household (58 to 76 years) , 5 pregnant women, 1 lactating woman, 6 older adults , Johnson Memorial Hospital at Nqutu, KwaZulu in South Africa. Older participants selected from household of women residing near the hospital , Study reported individual measurements. Erythrocyte folate < 151 ng/mL (WHO): 2/12 participants; erythrocyte folate < 160 ng/mL (author's cut‐off): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants , 6 weeks , Not specified , Enough so that each adult in the family would receive 500 μg folic acid/day , Microbiological assay with Lactobacillus casei (method of Hoffbrand et al 1966) , 500 μg/day , Haemoglobin, erythrocyte cell folate, serum folate , After 6 weeks, there was a significant rise in the erythrocyte folate concentration in 9 of the 12 subjects receiving the fortified food. Haemoglobin remained unchanged. Serum folate not reported due to wide variations.. Hertrampf 2003 , Wheat , Wheat flour fortified with folic acid and B‐vitamins , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service , 751 , 3 outpatient clinics in Santiago, Chile , Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% , approximately 1 year , Not specified , 2.2 mg/kg , QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) , 427 ± 18 μg/day , Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) , Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L . Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L. The prevalence of low serum and RBC folate was not significantly different.. Hirsch 2002 , Wheat , Wheat flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Free‐living adults >/= 70 years of age, with low income , 149 , 3 outpatient clinics in Santiago, Chile , Folate deficiency (serum folate < 6.8 nmol/L): 1.8% , 6 months , Not specified , 220 µg/100 g flour , Anion capture technique using Abbott Laboratories, Diagnostic Division, Abbot Park, IL , Not specified , Serum folate, haemoglobin, serum homocysteine, folate deficiency (< 6.8 nmol/L), hyperhomocysteinaemia , Serum folate increased from mean ± SD 16.2 ± 6.2 nmol/L to 32.7 ± 7.1 nmol/L. Homocysteine decreased from mean ± SD 12.95 ± 3.7 μmol/L to 11.43 ± 3.6 μmol/L. The prevalence of hyperhomocysteinaemia decreased from 31% to 17%.

    Concentration Assay:

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Cochrane Database of System atic Review s Fortification of w heat and m aize flour w ith folic acid for population health outcom es (Review ) Copyright © 2019 The Cochrane Collaboration.. Published by John W iley & Sons, Ltd. 84 baseline and follow-up) (58 to 76 years) 6 older adults participants selected from household of women residing near the hospital throcyte folate < 160 ng/ mL (author's cut-oI): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants ly would receive 500 μg folic acid/ day brand et al 1966) Hertrampf 2003 WheatWheat flour fortified with folic acid and B-vitamins Unontrolled before-andafter (same participants at baseline and follow-up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 7513 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/ kg QuantaPhase II Folate Assay kit (BioRad Laboratories, Hercules, CA) 427 ± 18 μg/ day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Haemoglobin remained unchanged.Haemoglobin remained unchanged.. Serum folate not reported due to wide variations Hertrampf 2003 Wheat Wheat flour fortified with folic acid and B‐vitamins Unontrolled before‐and‐after (same participants at baseline and follow‐up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 751 3 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/kg QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) 427 ± 18 μg/day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707..

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Colman 1974c , Maize , Maize flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Pregnant/lactating women (16 to 33 years), oldest women in household (58 to 76 years) , 5 pregnant women, 1 lactating woman, 6 older adults , Johnson Memorial Hospital at Nqutu, KwaZulu in South Africa. Older participants selected from household of women residing near the hospital , Study reported individual measurements. Erythrocyte folate < 151 ng/mL (WHO): 2/12 participants; erythrocyte folate < 160 ng/mL (author's cut‐off): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants , 6 weeks , Not specified , Enough so that each adult in the family would receive 500 μg folic acid/day , Microbiological assay with Lactobacillus casei (method of Hoffbrand et al 1966) , 500 μg/day , Haemoglobin, erythrocyte cell folate, serum folate , After 6 weeks, there was a significant rise in the erythrocyte folate concentration in 9 of the 12 subjects receiving the fortified food. Haemoglobin remained unchanged. Serum folate not reported due to wide variations.. Hertrampf 2003 , Wheat , Wheat flour fortified with folic acid and B‐vitamins , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service , 751 , 3 outpatient clinics in Santiago, Chile , Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% , approximately 1 year , Not specified , 2.2 mg/kg , QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) , 427 ± 18 μg/day , Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) , Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L . Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L. The prevalence of low serum and RBC folate was not significantly different.. Hirsch 2002 , Wheat , Wheat flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Free‐living adults >/= 70 years of age, with low income , 149 , 3 outpatient clinics in Santiago, Chile , Folate deficiency (serum folate < 6.8 nmol/L): 1.8% , 6 months , Not specified , 220 µg/100 g flour , Anion capture technique using Abbott Laboratories, Diagnostic Division, Abbot Park, IL , Not specified , Serum folate, haemoglobin, serum homocysteine, folate deficiency (< 6.8 nmol/L), hyperhomocysteinaemia , Serum folate increased from mean ± SD 16.2 ± 6.2 nmol/L to 32.7 ± 7.1 nmol/L. Homocysteine decreased from mean ± SD 12.95 ± 3.7 μmol/L to 11.43 ± 3.6 μmol/L. The prevalence of hyperhomocysteinaemia decreased from 31% to 17%.

    Diagnostic Assay:

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Cochrane Database of System atic Review s Fortification of w heat and m aize flour w ith folic acid for population health outcom es (Review ) Copyright © 2019 The Cochrane Collaboration.. Published by John W iley & Sons, Ltd. 84 baseline and follow-up) (58 to 76 years) 6 older adults participants selected from household of women residing near the hospital throcyte folate < 160 ng/ mL (author's cut-oI): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants ly would receive 500 μg folic acid/ day brand et al 1966) Hertrampf 2003 WheatWheat flour fortified with folic acid and B-vitamins Unontrolled before-andafter (same participants at baseline and follow-up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 7513 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/ kg QuantaPhase II Folate Assay kit (BioRad Laboratories, Hercules, CA) 427 ± 18 μg/ day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Haemoglobin remained unchanged.Haemoglobin remained unchanged.. Serum folate not reported due to wide variations Hertrampf 2003 Wheat Wheat flour fortified with folic acid and B‐vitamins Unontrolled before‐and‐after (same participants at baseline and follow‐up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 751 3 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/kg QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) 427 ± 18 μg/day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707..

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Colman 1974c , Maize , Maize flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Pregnant/lactating women (16 to 33 years), oldest women in household (58 to 76 years) , 5 pregnant women, 1 lactating woman, 6 older adults , Johnson Memorial Hospital at Nqutu, KwaZulu in South Africa. Older participants selected from household of women residing near the hospital , Study reported individual measurements. Erythrocyte folate < 151 ng/mL (WHO): 2/12 participants; erythrocyte folate < 160 ng/mL (author's cut‐off): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants , 6 weeks , Not specified , Enough so that each adult in the family would receive 500 μg folic acid/day , Microbiological assay with Lactobacillus casei (method of Hoffbrand et al 1966) , 500 μg/day , Haemoglobin, erythrocyte cell folate, serum folate , After 6 weeks, there was a significant rise in the erythrocyte folate concentration in 9 of the 12 subjects receiving the fortified food. Haemoglobin remained unchanged. Serum folate not reported due to wide variations.. Hertrampf 2003 , Wheat , Wheat flour fortified with folic acid and B‐vitamins , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service , 751 , 3 outpatient clinics in Santiago, Chile , Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% , approximately 1 year , Not specified , 2.2 mg/kg , QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) , 427 ± 18 μg/day , Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) , Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L . Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L. The prevalence of low serum and RBC folate was not significantly different.. Hirsch 2002 , Wheat , Wheat flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Free‐living adults >/= 70 years of age, with low income , 149 , 3 outpatient clinics in Santiago, Chile , Folate deficiency (serum folate < 6.8 nmol/L): 1.8% , 6 months , Not specified , 220 µg/100 g flour , Anion capture technique using Abbott Laboratories, Diagnostic Division, Abbot Park, IL , Not specified , Serum folate, haemoglobin, serum homocysteine, folate deficiency (< 6.8 nmol/L), hyperhomocysteinaemia , Serum folate increased from mean ± SD 16.2 ± 6.2 nmol/L to 32.7 ± 7.1 nmol/L. Homocysteine decreased from mean ± SD 12.95 ± 3.7 μmol/L to 11.43 ± 3.6 μmol/L. The prevalence of hyperhomocysteinaemia decreased from 31% to 17%.

    Clinical Proteomics:

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Cochrane Database of System atic Review s Fortification of w heat and m aize flour w ith folic acid for population health outcom es (Review ) Copyright © 2019 The Cochrane Collaboration.. Published by John W iley & Sons, Ltd. 84 baseline and follow-up) (58 to 76 years) 6 older adults participants selected from household of women residing near the hospital throcyte folate < 160 ng/ mL (author's cut-oI): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants ly would receive 500 μg folic acid/ day brand et al 1966) Hertrampf 2003 WheatWheat flour fortified with folic acid and B-vitamins Unontrolled before-andafter (same participants at baseline and follow-up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 7513 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/ kg QuantaPhase II Folate Assay kit (BioRad Laboratories, Hercules, CA) 427 ± 18 μg/ day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Haemoglobin remained unchanged.Haemoglobin remained unchanged.. Serum folate not reported due to wide variations Hertrampf 2003 Wheat Wheat flour fortified with folic acid and B‐vitamins Unontrolled before‐and‐after (same participants at baseline and follow‐up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 751 3 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/kg QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) 427 ± 18 μg/day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707..

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Colman 1974c , Maize , Maize flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Pregnant/lactating women (16 to 33 years), oldest women in household (58 to 76 years) , 5 pregnant women, 1 lactating woman, 6 older adults , Johnson Memorial Hospital at Nqutu, KwaZulu in South Africa. Older participants selected from household of women residing near the hospital , Study reported individual measurements. Erythrocyte folate < 151 ng/mL (WHO): 2/12 participants; erythrocyte folate < 160 ng/mL (author's cut‐off): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants , 6 weeks , Not specified , Enough so that each adult in the family would receive 500 μg folic acid/day , Microbiological assay with Lactobacillus casei (method of Hoffbrand et al 1966) , 500 μg/day , Haemoglobin, erythrocyte cell folate, serum folate , After 6 weeks, there was a significant rise in the erythrocyte folate concentration in 9 of the 12 subjects receiving the fortified food. Haemoglobin remained unchanged. Serum folate not reported due to wide variations.. Hertrampf 2003 , Wheat , Wheat flour fortified with folic acid and B‐vitamins , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service , 751 , 3 outpatient clinics in Santiago, Chile , Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% , approximately 1 year , Not specified , 2.2 mg/kg , QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) , 427 ± 18 μg/day , Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) , Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L . Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L. The prevalence of low serum and RBC folate was not significantly different.. Hirsch 2002 , Wheat , Wheat flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Free‐living adults >/= 70 years of age, with low income , 149 , 3 outpatient clinics in Santiago, Chile , Folate deficiency (serum folate < 6.8 nmol/L): 1.8% , 6 months , Not specified , 220 µg/100 g flour , Anion capture technique using Abbott Laboratories, Diagnostic Division, Abbot Park, IL , Not specified , Serum folate, haemoglobin, serum homocysteine, folate deficiency (< 6.8 nmol/L), hyperhomocysteinaemia , Serum folate increased from mean ± SD 16.2 ± 6.2 nmol/L to 32.7 ± 7.1 nmol/L. Homocysteine decreased from mean ± SD 12.95 ± 3.7 μmol/L to 11.43 ± 3.6 μmol/L. The prevalence of hyperhomocysteinaemia decreased from 31% to 17%.

    High Performance Liquid Chromatography:

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Cochrane Database of System atic Review s Fortification of w heat and m aize flour w ith folic acid for population health outcom es (Review ) Copyright © 2019 The Cochrane Collaboration.. Published by John W iley & Sons, Ltd. 84 baseline and follow-up) (58 to 76 years) 6 older adults participants selected from household of women residing near the hospital throcyte folate < 160 ng/ mL (author's cut-oI): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants ly would receive 500 μg folic acid/ day brand et al 1966) Hertrampf 2003 WheatWheat flour fortified with folic acid and B-vitamins Unontrolled before-andafter (same participants at baseline and follow-up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 7513 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/ kg QuantaPhase II Folate Assay kit (BioRad Laboratories, Hercules, CA) 427 ± 18 μg/ day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Haemoglobin remained unchanged.Haemoglobin remained unchanged.. Serum folate not reported due to wide variations Hertrampf 2003 Wheat Wheat flour fortified with folic acid and B‐vitamins Unontrolled before‐and‐after (same participants at baseline and follow‐up) Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service 751 3 outpatient clinics in Santiago, Chile Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% approximately 1 year Not specified 2.2 mg/kg QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) 427 ± 18 μg/day Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L .. Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L.Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707..

    Article Title: Fortification of wheat and maize flour with folic acid for population health outcomes
    Article Snippet: Colman 1974c , Maize , Maize flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Pregnant/lactating women (16 to 33 years), oldest women in household (58 to 76 years) , 5 pregnant women, 1 lactating woman, 6 older adults , Johnson Memorial Hospital at Nqutu, KwaZulu in South Africa. Older participants selected from household of women residing near the hospital , Study reported individual measurements. Erythrocyte folate < 151 ng/mL (WHO): 2/12 participants; erythrocyte folate < 160 ng/mL (author's cut‐off): 3/12 participants; Hb < 12.0 g/100L for nonpregnant women and <11.0 g/100L for pregnant women (WHO): 0/12 participants , 6 weeks , Not specified , Enough so that each adult in the family would receive 500 μg folic acid/day , Microbiological assay with Lactobacillus casei (method of Hoffbrand et al 1966) , 500 μg/day , Haemoglobin, erythrocyte cell folate, serum folate , After 6 weeks, there was a significant rise in the erythrocyte folate concentration in 9 of the 12 subjects receiving the fortified food. Haemoglobin remained unchanged. Serum folate not reported due to wide variations.. Hertrampf 2003 , Wheat , Wheat flour fortified with folic acid and B‐vitamins , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Women of reproductive age attending the Maternal and Infant Health Programme of the National Health Service , 751 , 3 outpatient clinics in Santiago, Chile , Low serum folate (< 3.2 nmol/L): 1.3%, low erythrocyte folate (< 181 nmol/L): 10.6% , approximately 1 year , Not specified , 2.2 mg/kg , QuantaPhase II Folate Assay kit (Bio‐Rad Laboratories, Hercules, CA) , 427 ± 18 μg/day , Serum folate, erythrocyte folate, low serum folate (< 3.2 nmol/L), low RBC folate (< 181 nmol/L) , Serum folate increased from mean ± SD 9.7 ± 4.32 nmol/L to 37.2 ± 9.6 nmol/L . Erythrocyte folate increased from mean ± SD 290 ± 102 nmol/L to 707 ± 179 nmol/L. The prevalence of low serum and RBC folate was not significantly different.. Hirsch 2002 , Wheat , Wheat flour fortified with folic acid , Unontrolled before‐and‐after (same participants at baseline and follow‐up) , Free‐living adults >/= 70 years of age, with low income , 149 , 3 outpatient clinics in Santiago, Chile , Folate deficiency (serum folate < 6.8 nmol/L): 1.8% , 6 months , Not specified , 220 µg/100 g flour , Anion capture technique using Abbott Laboratories, Diagnostic Division, Abbot Park, IL , Not specified , Serum folate, haemoglobin, serum homocysteine, folate deficiency (< 6.8 nmol/L), hyperhomocysteinaemia , Serum folate increased from mean ± SD 16.2 ± 6.2 nmol/L to 32.7 ± 7.1 nmol/L. Homocysteine decreased from mean ± SD 12.95 ± 3.7 μmol/L to 11.43 ± 3.6 μmol/L. The prevalence of hyperhomocysteinaemia decreased from 31% to 17%.



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